Aliens have wiped out Earth's men and are now looking to enslave the planet's women for their own hybridization program. Who's going to save the babes of Earth? Duke Nukem, that's who. Working with the Unified Babe Resistance, Duke must counteract the aliens through 14 levels of first-person search and destroy. He'll face mutant primates, Hoglodytes, Pig cops, and Octabrains with an awesome arsenal at his disposal, including such weapons as blasters, flamers, grenade launchers, and Duke's new weapon of choice, the .50 caliber Desert Eagle pistol.