This new sequel, fully titled Shin Gouketsuji Ichizoku: Toukon -Matrimelee- (新豪血寺一族 闘婚 -Matrimelee-) in Japan, brings back the roster from Power Instinct 2 (except Angela, Oshima, Sahad and Kinta, the latter of whom was replaced by his alter-ego, Pochi), plus 4 totally new characters and one new boss (Princess Sissy). However, all the characters introduced in Groove of Fight were discarded. Jimmy, Elias, Lynn and Jones from Rage of the Dragons are guest stars, and are unlockable. A few of the game elements were borrowed from that same game as well.

In the game's story, the King of Certain Country wants to find a worthy successor for the throne and the ideal husband for his little daughter (or a beautiful and strong woman for his older son) So he holds a fighting tournament where the prize is the hand of the princess and the throne succession.