Sango Fighter is a versus fighting game set in the Three Kingdoms era in China. The player can choose between five different characters from the time period, and fight other characters in either a one-on-one combat or a story mode.

The story is loosely based on real historical events of the Three Kingdoms era: towards the end of the Han Dynasty, China was controlled by the Emperor Ling, who was in turn controlled by ten of his servants in the royal palace. This created a convenient atmosphere for bandits, and the land was in turmoil. Then the Emperor ordered the ten dukes to take it on themselves to restore peace in the land, but the dukes instead fought amongst themselves. Finally, the duke Cao Cao took the Emperor captive and he now controls the realm. The player, however, must use five fighters to take on Cao Cao's forces and restore equilibrium to the land.