Star Trek: Away Team is turn-based strategy game taking place in an isometric view. The gameplay is influenced by other titles such as Commandos and X-Com. Players must coordinate the crew to solve various scenarios without being discovered by the guards or security system.

The game is set in the Star Trek universe, after the end of the Dominion War seen in the television series Star Trek: Deep Space Nine. It features a range of new characters, set on board the USS Incursion with voice appearances by Brent Spiner and Michael Dorn as Lieutenant Commander Data and Ambassador Worf, respectively.