The theme of the sequel is germ warfare, as the mercenary Mullins and his new partner Madeline Taylor travel to Colombia to investigate a viral outbreak in a small town, only to link it to a shadowy organization called Prometheus. The virus, called Romulus, is followed by a computer virus called Remus which is programmed to delete files on any computer in the world, in this case, files relating to Prometheus and Romulus, so an anti-virus cannot be formulated. Prometheus then plans to blackmail the G8 countries at a summit in Switzerland for billions of dollars. It is revealed throughout the course of the game that a mole inside The Shop may be feeding information to the terrorists.