Sly Cooper Thieves in Time continues to chronicle the adventures of the Sly Cooper gang from where Sly 3: Honor Among Thieves concluded. After completing their latest heist, Sly carries on with a case of alleged amnesia and dances off with gal pal Carmelita, leaving Bentley as the keeper of the treasured Thievius Raccoonus, The Cooper family's ancient book of master thievery. When Bentley discovers that pages of the book have begun to disappear in front of his eyes, he must round up the gang and save the Cooper Clan legacy from being destroyed forever.