Adam Crowley, a sorcerer living in London who was defeated in the first Nightmare Creatures, is close to achieving immortality. He has recently murdered Ignatius Blackward and Nadia Fransiscus, founders of the Circle, in order to obtain the magical artifact known as the Glymph. Players assume the role of Herbert Wallace, a man kidnapped at a young age by Adam Crowley who is now having visions about the recent events. On their quest to stop the evil sorcerer, players will combat more than 20 creatures with a number of weapons.