You select from Chris Redfield and Jill Valentine, two members of a special police force sent into the woods outside Raccoon City to investigate a series of strange murders. After being separated from their team, Chris and Jill begin searching through a mysterious house, hidden in a remote location deep within the forest. The characters encounter zombies, mutant plants, monstrous spiders, and other by-products of an experiment gone astray, as they attempt to gather evidence pertaining to the case, save their partners, destroy the evil residing within the house, and escape with their lives.