Marvel: Ultimate Alliance 2 (previously known as Marvel Ultimate Alliance 2: Fusion), a sequel to the 2006 action role-playing video game Marvel: Ultimate Alliance, was released September 15, 2009. The game was jointly developed by Vicarious Visions (PlayStation 3 and Xbox 360), n-Space (Nintendo DS, PlayStation 2 and Nintendo Wii) and Savage Entertainment (PlayStation Portable), and is published by Activision. The game features characters from the Marvel Comics universe and follows elements of the Secret War and Civil War story arcs.

The PlayStation 3 and Xbox 360 versions of Marvel Ultimate Alliance 2 were generally well received, averaging above 70% at aggregators GameRankings and Metacritic. The Nintendo DS, Nintendo Wii, PlayStation 2 and PlayStation Portable fared much poorer, averaging between 45% and 65% for their respective platforms.