The game features an all new single player campaign with 35 levels, an advanced campaign with 30 levels and an additional 5 unlockable levels. Finishing levels earns money which can be used to buy these new levels, new weapons, themes, hats, etc. Using Steam, the game has an automatic match making system and online matches are ranked in the global and friends leader boards. Players can control up to four worms per team with up to four teams per match.

Worms are fully customizable, including colour, hat, gravestone, victory dance, names, fort (for the fort game mode) and soundbank. All soundbanks of earlier Worms games are included with the addition of 20 new ones. Levels are also fully customizable. A simple drawing program allows the player to draw his own levels and simply apply a skin and automatically fill it up with hazards and worms, or carefully determine the exact position of everything manually. Levels can now also easily be made more vertical, for those who aren't afraid of some steep heights.