Puzzle Bots is a point-and-click adventure game about a group of tiny robots. It builds on the concept of the 2008 freeware adventure Nanobots by the same developer. The robots have been constructed by inventors at Dr. Hugo’s Factory for Making Robots. Each has a speciality, for instance Bomchelle is a female robot that throws (tiny, pink) bombs and Kelvin can heat stuff. But whenever the inventors aren’t looking, the robots escape their dome and go on an adventure in the factory.

One day they stumble onto an evil plan Dr. Hugo has in mind for the factory. They have to solve the mystery before he stops them in their tracks. The player takes control of each of the robots in turn, switching freely between them to get past the various hurdles.