In Moon, the year is 2058 and the United States has established a series of stations on the moon to perform scientific experiments and construct a Mars launch facility. An extraordinary discovery has been uncovered at one of the dig sites, a sealed hatch leading beneath the moon's surface. The player assumes the role of Major Kane, the leader of a special task force sent to investigate the mysterious hatch and reveal its secrets.

Moon Chronicles features first-person shooter gameplay and full 3D environments that the player can explore. Over the course of the game, the player can collect a variety of weapons to fight enemies.

The 3DS version is a remake of the original DS game, and has been released in an episodic format on the eShop.